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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPEN
All Species:
5.45
Human Site:
S1553
Identified Species:
24
UniProt:
Q96T58
Number Species:
5
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T58
NP_055816.2
3664
402248
S1553
L
E
R
K
E
E
D
S
D
F
I
S
G
R
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62504
3644
398736
S1568
L
E
R
K
S
E
E
S
D
F
P
P
G
R
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514992
1879
199498
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8SX83
5560
599981
D2967
V
D
D
D
N
S
V
D
M
D
E
A
G
R
A
Honey Bee
Apis mellifera
XP_395705
4346
474873
S1883
L
T
E
D
E
A
T
S
E
S
D
S
A
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784255
4378
488332
E2051
I
K
T
E
K
F
V
E
E
E
K
R
D
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
81.1
N.A.
N.A.
30
N.A.
N.A.
N.A.
N.A.
22.1
22.8
N.A.
20.7
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
87
N.A.
N.A.
37.8
N.A.
N.A.
N.A.
N.A.
35.9
38.4
N.A.
37.9
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
33.3
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
80
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
33.3
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
0
0
0
17
17
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
17
34
0
0
17
17
34
17
17
0
17
0
0
% D
% Glu:
0
34
17
17
34
34
17
17
34
17
17
0
0
0
0
% E
% Phe:
0
0
0
0
0
17
0
0
0
34
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
0
0
17
0
0
17
17
% I
% Lys:
0
17
0
34
17
0
0
0
0
0
17
0
0
0
0
% K
% Leu:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
17
17
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
34
0
0
0
0
0
0
0
0
17
0
67
0
% R
% Ser:
0
0
0
0
17
17
0
50
0
17
0
34
0
0
0
% S
% Thr:
0
17
17
0
0
0
17
0
0
0
0
0
0
0
17
% T
% Val:
17
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _